This week’s featured scholars at Murray State University are Dr. David R. Canning and Rebecca L. Cunningham ’14. Dr. Canning and Ms. Cunningham co-wrote the article, “Cell adhesion properties of neural stem cells in the chick embryo,” which appears in the May 2015 issue of the Open Access Journal, In Vitro Cellular & Developmental Biology – Animal.
The nervous system of vertebrates is derived from an early embryonic region referred to as the neural plate. In the chick embryo, the neural plate is populated by neural stem cells specified from the epiblast shortly after the onset of gastrulation. Accompanying the formation of the plate, chondroitin sulfate glycosaminoglycans are expressed in the basal extracellular matrix. We describe in vitro experiments measuring cell adhesion of epiblast cells during the formation of the neural plate. Our findings may suggest that neural stem cells are set apart from non-neural epiblast by changes in relative cell-cell and cell-substrate adhesion. Specifically, changes in cell adhesion separating neural stem cells from the non-neural epiblast may be augmented by the presence of exogenous chondroitin-6-sulfate in the epiblast basal lamina at the time neural progenitors are specified in the epiblast.
Cell adhesion properties of neural stem cells
in the chick embryo
By: Dr. David R. Canning and Rebecca L. Cunningham
In Vitro Cellular & Developmental Biology – Animal
May 2015, vol. 51 (5), pgs. 507-514
Dr. Teresa Betts, assistant Professor of Management at Murray State University, is our featured scholar this week. Dr. Betts co-authored the paper, “Beyond the trade-off and cumulative capabilities models: alternative models of operations strategy,” which appeared in volume 53, issue 13, of the International Journal of Production Research.
Organisations are expected to develop sound strategies relating to their core operations capabilities of cost efficiency, quality, delivery, flexibility and innovation, to gain and maintain competitive advantage. However, there is a paucity of specific models that can be used to explain and predict how organisations combine and use these capabilities. Previous research has primarily focused on the ‘trade-off’ and the ‘cumulative capabilities’ models. In this study, data from an international sample of 1438 manufacturing plants are used to explore other models that organisations are using in addition to the two predominant models. This analysis shows that, in practice, the trade-off model is not used, but the cumulative capabilities model is used extensively. Further, our proposed new models, the ‘threshold’, ‘average’ and ‘multiple’, are prevalent in many plants. Also, a small proportion of the plants have in place the ‘uncompetitive’ model. In terms of relative effectiveness, there are no significant differences between the models with respect to several measures of operational performance. Overall, this study provides empirical evidence that there are other operations strategy models beyond the trade-off and cumulative capabilities dichotomy that organisations deploy.
Beyond the trade-off and cumulative capabilities models: alternative models of operations strategy
By: Prakash J. Singh, Frank Wiengarten,
Alka A. Nand, and Teresa Betts
International Journal of Production Research
July 2015, vol. 53 (13), pgs. 4001-4020
Our Murray State University featured scholar this week is Dr. Jason R. Jaggers from the department of Applied Health Sciences. Dr. Jaggers’ article, “Aerobic and Resistance Training Improves Mood State among Adults Living with HIV,” appears in volume 36, issue 2, of the International Journal of Sports Medicine.
The purpose of this investigation was to examine the effects of combined aerobic and resistance exercise training among self-reported mood disturbances, perceived stress, frequency of self-reported symptoms, and symptom distress in a sample of HIV + adults. For this purpose, 49 participants were randomly assigned into an exercise (EX) or control (CON) group. Those in the EX group completed 50 min of supervised aerobic and resistance training at a moderate intensity twice a week for 6 weeks. The CON group reported to the university and engaged in sedentary activities. Data were collected at baseline before randomization and 6 weeks post intervention. Measures included the symptom distress scale (SDS), perceived stress scale (PSS), profile of mood states (POMS) total score, and the POMS sub-scale for depression and fatigue. A 2 way ANOVA was used to compare between and within group interactions. The EX group showed a significant decrease in reported depression scores (p = 0.03) and total POMS (p = 0.003). The CON group reported no change in POMS or SDS, but showed a significant increase in PSS. These findings indicate that combination aerobic and resistance training completed at a moderate intensity at least twice a week provides additional psychological benefits independent of disease status and related symptoms.
Aerobic and Resistance Training Improves Mood State among Adults Living with HIV
By: Jason R. Jaggers, Hand, G. A., Dudgeon, W. D.,
Burgess, S., Phillips, K.D., Durstine, J.L., and Blair, S. N.
International Journal of Sports Medicine
Feb. 2015, vol. 36 (2), pgs. 175-181